Qhov twg yogBlwm yam,Quercetin lubFpuas yog?
Quercetinthiabfisetinyog ob qho tib si zoo -paub natural compounds. Lawv ob leeg koom nrog hauv chav kawm flavonoid thiab muaj ntau yam kev ua ub no lom neeg. Txawm li cas los xij, lawv kuj qhia qhov txawv ntawm ntau yam. Niaj hnub no, cia peb delve rau hauv lawv qhov zoo sib xws thiab qhov sib txawv.
1. Covzoo sib xwsnruab nrab quercetin thiabfisetin
(1)Core chemical structures yog homologous:
Ob leeg muaj nyob rau hauv subcategory ntawm "flavonols". Lawv cov pob txha yooj yim yog tag nrho ntawm peb lub nplhaib - cov qauv zoo li (A, C, thiab B rings), thiab cov qauv no yog lub hauv paus rau lawv lub peev xwm antioxidant.
(2)Muaj zog antioxidant thiab tiv thaiv -kev ua ub no:
1) Lawv yog cov muaj zog antioxidants thiab feem ntau ua haujlwm los ntawm ob txoj hauv kev:
Ncaj qha tshem tawm cov dawb radicals:Nws tuaj yeem cuam tshuam ncaj qha rau cov tsis ruaj khov dawb radical molecules hauv lub cev uas tuaj yeem ua rau cov hlwb thiab DNA puas.
Activating endogenous antioxidant txoj kev:Qhov no yog ib qho tseem ceeb dua mechanism. Ob leeg tuaj yeem qhib txoj hauv kev "Nrf2" hauv lub cev. Nrf2 yog "tus tswv hloov pauv" ntawm cov lus teb ntawm tes. Thaum ua haujlwm, nws pib qhia txog cov noob caj noob ces, tsim cov tshuaj tua kab mob muaj zog uas tib neeg lub cev muaj, xws li glutathione thiab superoxide dismutase (SOD).
2) Los tiv thaiv -inflammatory: Los ntawm inhibiting qhov tseem ceeb inflammatory signaling txoj kev xws li NF-κB thiab txo cov zus tau tej cov pro-inflammatory cytokines, nws alleviates mob o ntawm cov hauv paus hniav. Cov kab mob rhiab heev yog lub hauv paus rau yuav luag txhua yam kab mob.
(3) Txhawb nqa cell noj qab haus huv thiab autophagy
Ob leeg tau raug pov thawj los ua rau autophagy. Nws yog ib qho tseem ceeb rau kev tswj hwm cell noj qab haus huv, ncua kev laus, thiab tiv thaiv cov kab mob neurodegenerative.
(4) Muaj peev xwm tiv thaiv -aging zog:
Ntxiv rau qhov tsis ncaj ncees ncua kev laus los ntawm kev tiv thaiv oxidation thiab tiv thaiv -mob, lawv txhua tus tau lees paub los ntawm kev tshawb fawb kom muaj peev xwm inhibit qhov kev laus ntawm -txog -galactosidase (SA- -GAL), uas yog ib qho cim ntawm cellular aging. Qhov tseem ceeb tshaj, lawv txhua tus suav tias yog Senolytics muaj peev xwm (senescent cell scavengers), uas yog, lawv tuaj yeem xaiv ua rau kev tuag ntawm cov hlwb senescent (cov hlwb no tsis sib faib, zais cov tshuaj phem thiab ua kom cov laus).
(5) Qhov chaw:
Ob leeg muaj nyob rau hauv cov txiv hmab txiv ntoo thiab zaub thiab yog ib qho ntawm cov laj thawj tseem ceeb vim li cas noj zaub mov noj qab haus huv (xws li Mediterranean noj) tuaj yeem txhawb kev noj qab haus huv.
2.Qhov sib txawv tseem ceeb ntawm fisetin thiab quercetin
(1). Kev tiv thaiv - kev ua xua thiab kev tiv thaiv kab mob: Quercetin daim ntawv kos npe
Quercetin: Lub npe hu ua "natural antihistamine". Nws tuaj yeem ua kom ruaj khov ntawm cov cell membrane ntawm mast hlwb, inhibit lawv cov degranulation, thiab yog li tiv thaiv kev tso tawm ntawm kev tsis haum tshuaj xws li histamine thiab leukotrienes. Qhov no muaj txiaj ntsig zoo hauv kev txo cov tsos mob xws li kev ua xua raws caij nyoog (thaum ua npaws), mob hawb pob, thiab urticaria, thiab nws yog ib qho zoo tshaj plaws thiab tseem ceeb.
Fisetin: Txawm hais tias nws tseem muaj cov tshuaj tiv thaiv kab mob -, nws cov txiaj ntsig thiab kev tshawb fawb txhawb nqa ncaj qha thiab sai inhibiting kev tsis haum tshuaj yog qhov tseeb tsawg dua li cov quercetin. Qhov no tsis yog qhov tseem ceeb ntawm kev sib ntaus sib tua ntawm fiseketone.
(2). Lub hlwb noj qab haus huv thiab kev paub muaj nuj nqi: Lub hnub qub theem ntawm Fiserone
Fiserone:Dav suav hais tias yog ib qho ntawm cov muaj zog tshaj plaws Nrf2 activators paub txog hnub no. Fiserone tuaj yeem ua kom txoj hauv kev no hauv lub hlwb, muab kev tiv thaiv tob. Ntau qhov kev tshawb fawb preclinical tau pom tias nws tuaj yeem:
1) Txhawb kev tsim ntawm ntev - lub sijhawm nco.
2) Ua kom nce qib ntawm lub hlwb- muab tau los ntawm neurotrophic factor (BDNF), uas yog "chiv" rau kev noj cov paj hlwb.
3) Nws cuam tshuam txog hnub nyoog- cuam tshuam txog kev nco qab poob qis thiab qhia tau tias muaj peev xwm tiv thaiv tau zoo hauv cov qauv ntawm cov kab mob neurodegenerative xws li Alzheimer's thiab Parkinson's.
4) Nws muaj peev xwm ua tau zoo tshem tawm cov hlwb hauv lub hlwb yog suav tias yog lub luag haujlwm tseem ceeb rau nws txoj kev tiv thaiv - kev laus ntawm lub hlwb.
Quercetinkuj tseem muaj qee yam kev tiv thaiv neuroprotective, feem ntau los ntawm nws cov antioxidant thiab tiv thaiv -cov khoom ua rau mob. Txawm li cas los xij, lub zog thiab qhov tshwj xeeb ntawm cov pov thawj rau nws lub luag haujlwm hauv kev txhim kho kev nco thiab tshwj xeeb tiv thaiv cov neurons tam sim no qis dua cov fiseketone.
(3). Anti-aging thiab Senolysis (tshem tawm ntawm senescent hlwb): Fiserone zoo dua
Fiserone: Hauv kev tshawb fawb Senolytics, fiserone tau suav tias yog lub hnub qub ci ntsa iab. Nws tau raug pov thawj tias yog ib qho muaj zog thiab dav -spectrum senescent cell scavenger. Hauv kev sim tsiaj txhu, kev siv fiserone ib leeg tuaj yeem txo qis ntawm cov cell load hauv ntau cov ntaub so ntswg (xws li lub siab, ob lub raum, thiab lub hlwb), thiab txuas ntxiv kev noj qab haus huv ntawm cov qauv, tsis yog tag nrho lub neej.
Quercetin: Nws yog ib qho tseem ceeb ntawm Senolytic "cocktail therapy" thaum ntxov (quercetin + cov tshuaj tiv thaiv - mob qog noj ntshav dasatinib), qhia nws lub peev xwm los tshem tawm cov hlwb senescent. Txawm li cas los xij, hais txog qhov dav ntawm -spectrum kev ua tau zoo thiab kev ua tau zoo, cov kev tshawb fawb tam sim no feem ntau qhia tias fetherazone monotherapy muaj qhov muaj zog dua thiab muaj peev xwm ntau dua.
(4). Kev noj qab haus huv plawv: Cov pov thawj rau quercetin yog qhov ruaj khov dua
Quercetin: Nws tau kawm ntau yam hauv kev kho mob plawv. Nws tau raug pov thawj tias muaj peev xwm:
1) Nws txhim kho vascular endothelial muaj nuj nqi, txhawb kev tso tawm ntawm nitric oxide (NO), dilates cov hlab ntsha, thiab pab txo cov ntshav siab.
2) Inhibiting the oxidation of low-density lipoprotein (LDL) yog ib kauj ruam tseem ceeb hauv kev tiv thaiv kev tsim cov atherosclerotic plaques.
3) Nws muaj peev xwm tiv thaiv platelet aggregation.
Fiserone: Nws kuj muaj txiaj ntsig zoo rau cov hlab plawv, tab sis cov txheej txheem ntawm nws qhov kev ua thiab kev ruaj khov ntawm cov pov thawj, tshwj xeeb tshaj yog nyob rau hauv tib neeg kev sim tshuaj, tam sim no tsis txaus thiab ncaj qha raws li cov quercetin.
(5). Kev ua kis las thiab kev rov zoo: Muaj kev tshawb fawb ntxiv ntawm quercetin
Quercetin: Kev kawm dav dav rau kev txo qis oxidative kev nyuaj siab thiab mob tshwm sim los ntawm kev tawm dag zog, nws tuaj yeem pab txo qis qhov mob tshwm sim (DOMS) thiab ua kom rov zoo tom qab qoj ib ce.
Fisetin: Kev tshawb fawb hauv daim teb no kuj tsis tshua muaj thiab nws tsis yog nws cov lus qhia tseem ceeb.
(6). Kev noj qab haus huv metabolic: Ob leeg muaj peev xwm, thiab fetherone yog qhov tshiab
Ob leeg muaj peev xwm txhim kho cov tshuaj insulin thiab tswj cov ntshav qab zib.
Fiserone tau pom cov txheej txheem tshwj xeeb thiab cov txiaj ntsig tau zoo hauv qee qhov kev tshawb fawb, tshwj xeeb tshaj yog hauv kev txo qis cov rog hauv cov hlab ntsha thiab txhim kho cov kab mob metabolic, thiab tej zaum yuav muaj qhov me me.
3.Qhov twg zoo dua, quercetin lossis fisetin?
Kev xaus: Tsis muaj qhov "zoo dua", tsuas yog "tsim dua".
Quercetin tuaj yeem yog qhov kev xaiv zoo dua hauv cov xwm txheej hauv qab no:
Tswj cov teeb meem tsis haum:Yog tias koj muaj kev fab tshuaj raws caij nyoog (thaum ua npaws), ua xua rhinitis lossis mob hawb pob, quercetin yog thawj qhov kev xaiv meej. Nws lub ntuj antihistamine muaj txiaj ntsig zoo thiab muaj qee qhov kev phiv.
Txhawb kev noj qab haus huv ntawm lub plawv:Yog tias koj muaj keeb kwm ntawm tsev neeg lossis kev pheej hmoo ntawm ntshav siab, arteriosclerosis lossis cov roj cholesterol siab, quercetin muaj cov pov thawj ncaj qha thiab ntau ntau los txhawb nws.
Kev tawm dag zog rov qab:Yog tias koj yog ib tus neeg ncaws pob lossis nquag koom nrog kev kawm siab - siv zog, quercetin muaj qhov zoo dua hauv kev txo cov leeg mob thiab ua kom rov zoo dua.
Broad -spectrum kev kho mob txhua hnub:Vim nws muaj ntau yam, quercetin yog tus nqi - xaiv tau zoo thiab nyab xeeb raws li cov tshuaj antioxidant thiab tiv thaiv - inflammatory ntxiv rau kev siv txhua hnub.
Fiserone tuaj yeem yog qhov kev xaiv zoo dua hauv cov xwm txheej hauv qab no:
Lub hlwb noj qab haus huv thiab kev txawj ntse muaj nuj nqi:Yog tias koj lub hom phiaj tseem ceeb yog los tiv thaiv- kev laus, txhim kho kev nco, thiab tiv thaiv lossis pab txhawb cov kab mob neurodegenerative (xws li Alzheimer's kab mob), fiseketone yog undoubtedly tam sim no "hnub qub". Nws lub peev xwm ua kom muaj zog Nrf2 thiab cov teebmeem tshwj xeeb hauv lub paj hlwb muab nws sib nrug.
Sib sib zog nqus los tiv thaiv-aging thiab tshem tawm cov hlwb senescent:Yog tias koj lub hom phiaj yog mus rau "Senolytic therapy" kom tshem tawm cov hlwb tsis zoo thiab ua kom cov txheej txheem kev laus tag nrho ntawm lub cev, kev ua tau zoo thiab dav -spectrum cov khoom qhia los ntawm fiserone hauv cov kev tshawb fawb preclinical ua rau nws zoo dua li quercetin. Nws feem ntau suav hais tias yog ib qho kev cog lus zoo tshaj plaws ntawm Senolytics tam sim no.
Metabolic noj qab haus huv thiab rog poob:Txawm hais tias ob qho tib si muaj txiaj ntsig zoo, qee qhov kev tshawb fawb ntawm cov txheej txheem uas fiserone txhim kho cov metabolism hauv kev noj qab haus huv thiab txo cov roj visceral tuaj yeem tsim kho tshiab.
Synergy: 1+1 > 2
Qhov tseeb, kev siv ua ke ntawm quercetin thiab fisetin tuaj yeem ua rau muaj kev sib koom ua ke. Lawv ua haujlwm los ntawm txoj hauv kev zoo sib xws tab sis txawv me ntsis, thiab thaum siv ua ke, lawv tuaj yeem muab cov tshuaj tua kab mob antioxidant, tiv thaiv - mob thiab tiv thaiv kev laus - kev tiv thaiv kev laus.
Yog li ntawd, xaiv qhov uas haum koj zoo tshaj plaws raws li koj qhov xwm txheej tiag tiag yog qhov zoo tshaj plaws.
Xi'an Season Biotechnology tshwj xeeb hauv R & D Ntau lawm thiab muag cov nroj tsuag ntuj extract thiab kev noj qab haus huv ntxiv tshaj 10 xyoo hauv Suav teb, nrog kev nplua nuj tuaj yeem xa tawm mus rau lub ntiaj teb los ntawm huab cua lossis hiav txwv.
Yog tias koj tab tom nrhiav rau qhov zoo fisetin hmoov lossis quercetin hmoov, pls xav tiv tauj peb.
Hu rau cov ntsiab lus:
Tian
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